GELCIDE - locally-delivered antibiotic for Periodontal Pockets Treatment

Gelcide consists of a patented solution of piperacillin and tazobactam paired with a carrier that effectively dispenses the potent active formula right to the bottom of the dental pocket or the wound. The local-delivery application minimizes some of the problems of systemic antibiotics, such as side effects and increased bacterial resistance.

Because it is applied directly as a liquid to the affected area, Gelcide is particularly suitable for preventing damage to the surrounding bone. Its unique formula allows it to rapidly penetrate into the pocket and subsequently gelify inside, while, on the surface, it creates a strong external film that virtually seals the wound. These capabilities allow for easy application while ensuring that the active ingredients are retained at the infection site.

Current SRP treatments are rendered less effective because of poor patient compliance. They place the burden of treatment on patients themselves, expecting them to self-administer antibiotics up three times a day off site. Gelcide allows the practitioner full control of the treatment process, and as a result increases the certainty of treatment outcomes.

Gelcide’s exclusive formula is slowly released at effective concentrations for up to 8–10 days. The film is permeable but insoluble to fluids – protecting the pocket from further oral-bacteria exposure, subsequent irritation and infection.

This patented solution offers you an effective way of complementing standard SRP treatment. It will improve success rates, help prevent early body reabsorption and potential displacements – resulting in increased therapy compliance and more satisfied patients.

Why Gelcide?

Ease of Application:

  • Fluid mix that penetrates deep into the dental pocket.
  • Once applied, Gelcide ‘seals’ the pocket, solidifying as a gel after contact with fluids, thereby remaining in the pocket and acting as a film when making contact with air at the gingival level.
  • No need for additional injection devices: all elements are included.
  • No need to worry about patient compliance: all work can be carried out on site.

Improved Effectiveness over Time:

  • Highly effective against a broad range of gram+ and gram- bacteria through antibiotic activity of piperacillin.
  • Beta lactamase-induced bacterial resistance is prevented through coadministration of tazobactam.
  • Biodegradable and anti-microbial active for 8-10 days.
  • Once opened, remains active for 4 weeks.


Patient Benefits:

  • No side effects due to 100-fold higher levels of concentration of active agent in subgingival site compared to systemic therapy.
  • Slow-release mechanism and complete on-site treatment eliminate need for patients to follow up treatment off site.
  • Unique film means patients do not need to adapt eating or drinking habits throughout duration of treatment.

Treatment and Practice Benefits:

  • Increased treatment compliance as doctor has higher control of the therapy.
  • Dentist builds trust and loyalty by offering most up-do-date treatments that mean far less intrusion in patient’s day-to-day life.
  • Incremental revenue with low incremental workload.

How to use

Aspirate all the solution using the syringe with needle.

Inject the solution into the powder bottle.

Shake the bottle until the powder is fully dissolved.

Take a suitable amount of solution for the use.

Substitute the syringe needle with the blunted one to apply the solution.

For periodontal pockets: To apply the solution, bend the blunted needle to mimic a periodontal probe, and then explore the pocket in a manner similar to periodontal probing. Place the tip of the needle near the base of the pocket and inject the product until the solution reaches the upper margin of the gingiva. Pull the needle out of the pocket.

Direct an air stream on the freshly applied solution (for about 10 seconds) to help the evaporation of the solvent and the adhesion of the film on the application site.

For the treatment of incisions, injures, sutures and any other interruptions of oral mucosa that have to be protected, apply the film-forming solution once it has been properly dried.

Write the date on the bottle. In the patient’s file you should record the date of administration and batch number to ensure adequate traceability of the product.

Caution! The unused solution, if stored far from light at 4°C keeps its efficacy for 4 weeks.